Research projects in our group address different aspects of retroviral and influenza virus (IAV) biology. A long-term interest of the group is the formation and architecture of the infectious human immunodeficiency virus (HIV) particle. A major current focus in the lab is the study of entry and post-entry stages in the life cycle of HIV‑1 and murine leukemia virus and the role of innate immune responses in these processes. We combine conventional and super-resolution microscopy as well as correlative-light and electron microscopy (CLEM) to study the composition and architecture of entering subviral complexes and the interaction with cellular proteins and structures.
Our main research interests are: