Prof. Dr. Dr. h.c. Hans-Georg Kräusslich
hans-georg.kraeusslich
(at)med.uni-heidelberg.de
Phone: +49 6221 56–5001
Fax: +49 6221 56–5003
Retroviral and Influenza Virus (IAV) Biology
Projects
Research projects in our group address different aspects of retroviral and influenza virus (IAV) biology. A long-term interest of the group is the formation and architecture of the infectious human immunodeficiency virus (HIV) particle. A major current focus in the lab is the study of entry and post-entry stages in the life cycle of HIV‑1 and murine leukemia virus and the role of innate immune responses in these processes. We combine conventional and super-resolution microscopy as well as correlative-light and electron microscopy (CLEM) to study the composition and architecture of entering subviral complexes and the interaction with cellular proteins and structures.
Our main research interests are:
Morphogenesis and structure of HIV
Post-entry stages in retroviral replication
Role of lipids in virus replication